Formulation Lab

Built for the formulator's bookmarks bar.

Per-active analytical scope, INCI verification, recommended use levels, carrier-compatibility guidance, and stability data — the references a cosmetic chemist actually wants on tap when designing a serum, cream, or eye-area finished product.

Sample lot PD-26-A0517 · Copper Tripeptide-1 · Pepoderma atelier · Shanghai

Documented like a paper, sold like an active

Every batch, fully documented.

Every shipment leaves the atelier with the batch's Certificate of Analysis, HPLC purity, mass-spec identity, and microbial limits. INCI verification, stability data in our reference aqueous serum, and copper-content verification (for copper-peptide actives) are included so a chemist answers their own QA before the first sample fills a laboratory beaker.

≥99%

HPLC + ESI-MS purity

100%

Batches with COA

<12h

First response

INCI verification + CAS reproduced on every SDS so cosmetic-notification workflows (CPNP, equivalent) run in parallel.

RP-HPLC + ESI-MS on every batch, plus copper-content verification on the copper-peptide actives by atomic absorption.

Stability in our reference aqueous serum documented per active; accelerated and long-term data available on request.

View sample COA (PDF)Read our analytical methods

Analytical methods · on every lot

What every Pepoderma release is tested for.

The release scope below runs on every commercial cosmetic- grade lot. Method provenance follows USP <621> (HPLC), EP cosmetic-ingredient frameworks, and ICH Q2 method validation. The lot report carries the numerical value, the method line, and the release decision against the documented target.

Test	Method	Target	Why we run it
RP-HPLC purity	C18 gradient with UV detection at the active's working wavelength	≥ 98.0 % (cosmetic-grade spec)	Resolves the synthesised active from synthesis truncations and late-eluting impurities. The chromatogram is attached to every lot report.
ESI-MS identity	ESI-MS, monoisotopic [M+H]⁺ vs. theoretical	Confirmed (±0.5 Da)	Confirms molecular weight of the peptide active matches the labelled INCI molecule.
INCI verification	Cross-reference against EU CosIng + US PCPC INCI databases	Listed INCI · SDS bound	The lot SDS carries the verified INCI name + CAS so brand notification workflows (CPNP, equivalents) can rely on the document directly.
Water content (Karl Fischer)	Coulometric KF	≤ 8.0 % (lyophilised powder)	Lyophilisation control. Out-of-spec water shortens the working shelf life of the active in finished products.
Counter-ion	Ion chromatography	Acetate (default)	Acetate is the default cosmetic-grade salt; alternative counter-ions are documented on the SDS when present.
Stability — reference aqueous serum	Time-course RP-HPLC at 25 °C / 40 °C over 12 months	Documented decay envelope; ≥ 90 % retention at 6 months / 25 °C	Establishes a baseline shelf-life expectation in a representative cosmetic carrier. Brand-specific carrier-stability is scoped per inquiry.
Photo-stability flag	Light-stress study (ICH Q1B-style)	Flagged on the lot report when relevant	Active-class-specific. Copper-peptide actives in particular need light-protected packaging guidance for the brand owner.

Documentation

Everything a cosmetic R&D chemist needs.

Every lot ships with the documentation panel on the right. On request we provide raw HPLC chromatograms, ESI-MS spectra, the extended stability series, and the SDS bundled with the verified INCI name for cosmetic notification workflows.

Lot Report

Per-lot release document with HPLC purity, ESI-MS identity, water content, counter-ion, and stability flag.

RP-HPLC chromatogram

Raw chromatogram showing main peak + integrated impurity profile.

ESI-MS spectrum

[M+H]⁺ confirmation within ±0.5 Da of theoretical INCI molecule.

Stability data

Reference aqueous-serum stability across 25 °C / 40 °C through 12 months on the lot report; brand-carrier study scoped per inquiry.

INCI + CAS SDS

Verified INCI name and CAS on the lot SDS, ready for cosmetic-notification workflows (CPNP, NMPA, equivalents).

Carrier-compatibility note

Active-specific flags: chelator-free water, working pH range, reductive-antioxidant placement, preservative-system compatibility.

Let's talk peptides.

First response under 12 hours · Catalog · Sample COA · MOQ · Lead time. Our regulatory and atelier teams review every inquiry before pricing.