Test it yourself. If it fails, you get a full refund.
Independent test fails? Full refund.
Independent test fails? Full refund.
10 vials per kit, from 1 kit per product and strength. We reply to every quote request within 24 hours. How quotes work →
10 vials per kit · from 1 kit · reply within 24 hours Quotes →
10 vials per kit · from 1 kit Quotes →
Acadesine: the β-D-riboside of 5-aminoimidazole-4-carboxamide, a nucleoside
Research topic: Body & metabolism · group: Lipid metabolism and auxiliaries
AICAR, as listed in our product table, is acadesine: 5-aminoimidazole-4-carboxamide joined to β-D-ribose, a nucleoside often written AICAr. It is not a peptide. Inside cells it can be phosphorylated to the ribotide ZMP, which part of the literature also abbreviates AICAR, but which is a separate compound with a phosphate group, its own formula and its own CAS; the fact table refers to the riboside. On this site it joins the auxiliary materials of the body-composition and metabolic page, beside MOTS-c. The studies in our product data cover endurance tests in mice, the disposition of acadesine in a few volunteers, a randomised trial in coronary bypass surgery, a phase I/II study in chronic lymphocytic leukaemia, and a systematic review of its AMPK-dependent and independent actions.
Besides the vials, 5-Aminoimidazole-4-carboxamide riboside (AICAR) is bottled as a nasal spray, held in stock in the United States and shipped from there.
The COA of every lot of 5-Aminoimidazole-4-carboxamide riboside (AICAR) reports:
Ask for the COA of the batch you are quoted; the batch number on it is the batch we ship.
Independent test fails? Full refund. How the refund works
| Field | Value | Source |
|---|---|---|
| Chemical name | 5-Aminoimidazole-4-carboxamide riboside (AICAR) | Our product table |
| Other names | AICAr · Acadesine · AICA riboside · SCH-900395 · NSC-105823 | Our product table |
| Molecular formula | C9H14N4O5 | Our product table |
| Molecular weight | 258.23 g/molβ-D-riboside (acadesine), not the phosphorylated ribotide, as the formula shown | Our product table |
| CAS number | 2627-69-2 | Our product table |
| Strengths (per vial) | 50 mg, 100 mg | Our product table |
| Kit and minimum order | 10 vials per kit · from 1 kit per strength | Our product table |
| Form | Lyophilized powder | Our product table |
| Catalogue codes | 50 mg: AICAR50 · 100 mg: AICAR100 | Our product table |
| Purity specification | ≥ 99.0% (HPLC)Specification; the measured value is on the COA of the lot. | Our product table |
| Appearance | White to off-white lyophilized powder | Our product table |
| Storage | Store at 2–8 °C, protected from light and moisture | Our product table |
| Batch COA | HPLC purity · MS identity · endotoxin · fill — every lot | Our batch COA |
Product-table values checked 2026-10-09. The measured values of a lot are on its COA.
| First author / trial | Year | Journal | What was studied | Record |
|---|---|---|---|---|
| Narkar VA | 2008 | Cell | AMPK and PPARδ agonists, AICAR among them, in endurance tests in mice | PubMed 18674809 |
| Dixon R | 1993 | J Clin Pharmacol | Disposition and metabolism of acadesine in a small study in human volunteers | PubMed 8227467 |
| Newman MF | 2012 | JAMA | Acadesine in a randomised trial in coronary artery bypass surgery (RED-CABG) | PubMed 22782417 |
| Van Den Neste E | 2013 | Cancer Chemother Pharmacol | Acadesine in a phase I/II study in relapsed or refractory chronic lymphocytic leukaemia | PubMed 23228986 |
| Visnjic D | 2021 | Cells | Systematic review of AMPK-dependent and AMPK-independent actions of AICAr | PubMed 34064363 |
Studies recorded in our product data (checked 2026-10-09). They show what has been researched with this molecule — the materials and models of each study — and are not a statement about the vials we supply.
What to put in your quote request
With these facts the first reply can carry the unit price per kit, shipping and lead time.
No. The vials hold the riboside (acadesine, AICAr). ZMP, also called AICA ribotide, is its 5′-phosphate, formed inside cells; it carries a phosphate group and has a different formula and CAS number.
The β-D-riboside, the stereochemically defined record our product data follow. A deposited structure without stereochemistry and the phosphorylated ribotide are kept apart, and the identity test of each lot is read against the β-D form.
One kit is 10 vials of the same product at the same strength. Each vial holds the stated amount, for example 10 mg of lyophilized peptide; the few solutions are stated per vial in mg or ml. 1 kit per product and strength. One order can combine several products and strengths, each from 1 kit.
HPLC purity, MS identity, endotoxin and fill, on the COA of every lot of a stocked peptide. The COA carries the lot number, so you can match it to the vials you receive. Yes. Ask for the COA of the batch you are quoted; the batch number on that COA is the batch we ship.
In writing, per request. Prices are tiered by the number of kits of each peptide and strength; the quotation gives the unit price per kit, the shipping cost and the lead time. We reply within 24 hours.
Because listings describe different forms: a free peptide or a salt (acetate, TFA), a copper complex or its free peptide, one peptide or a two-peptide material — and some registries keep older numbers. Each product page says which form its values refer to; the COA of the lot is the reference.
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