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Research topic
Signal, neurotransmitter-modulating and copper peptides, KPV and the other skin-research peptides — by chemical name, in sealed vials sold by the kit of ten.
This topic gathers the peptides studied in skin and skin-ageing research: the palmitoylated signal peptides of the Matrixyl® family, the SNARE-related hexa- and octapeptides, the copper tripeptides GHK-Cu and AHK-Cu, and KPV, the C-terminal tripeptide of α-MSH. Every product page opens with the chemical name, gives the trade name where one exists, and lists sequence, formula, mass and CAS with the source of each value.
The stocked peptides carry catalogue codes and a batch COA for every lot; the others are listed by chemical name and quoted on request. The four groups below follow the peptide classes described in the literature, and each has a page of its own.
Palmitoyl Pentapeptide-4 (Matrixyl®), Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7 (Matrixyl® 3000), Palmitoyl Tripeptide-38 and Palmitoyl Hexapeptide-12 — palmitoylated peptides described as signal peptides in the literature cited on each page.
Grouped as signal peptides where the review by Gorouhi and Maibach (2009) or a paper on the peptide itself describes them so.
5-mer
Matrixyl®
Palmitoyl Pentapeptide-4 (Pal-Lys-Thr-Thr-Lys-Ser)
Matrixyl® 3000
Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7, a two-peptide material
Matrixyl® synthe'6®
Palmitoyl Tripeptide-38, a palmitoylated tripeptide
6-mer
Palmitoyl Hexapeptide-12 (Pal-Val-Gly-Val-Ala-Pro-Gly)
Acetyl Octapeptide-3 (SNAP-8®), Acetyl Hexapeptide-8 (Argireline®), Pentapeptide-18 (Leuphasyl®) and Dipeptide Diaminobutyroyl Benzylamide Diacetate (SYN®-AKE).
Grouped by the papers cited on each page; Acetyl Octapeptide-3 by its sequence, which extends Acetyl Hexapeptide-8.
8-mer
SNAP-8®
Acetyl Octapeptide-3, an N-acetylated, amidated octapeptide
6-mer
Argireline®
Acetyl Hexapeptide-8, an N-acetylated, amidated hexapeptide
SYN®-AKE
Dipeptide Diaminobutyroyl Benzylamide Diacetate, a small synthetic peptide derivative
Leuphasyl®
Pentapeptide-18 (Tyr-D-Ala-Gly-Phe-Leu)
GHK-Cu and AHK-Cu (copper(II) complexes), and GHK, the copper-free tripeptide.
Copper(II) complexes by their formula in our product table, plus the copper-free tripeptide GHK.
3-mer
Copper(II) complex of the tripeptide Ala-His-Lys
3-mer
Copper(II) complex of the tripeptide Gly-His-Lys
3-mer
The tripeptide Gly-His-Lys, without copper
KPV, the α-MSH C-terminal tripeptide, with Acetyl Tetrapeptide-5, Palmitoyl Tripeptide-5, Nonapeptide-1, Acetyl Hexapeptide-1, Carnosine, Dipeptide-2 and more, listed by chemical name and sequence.
Peptides without a cited source for one of the classes above.
3-mer
Lys-Pro-Val, the C-terminal tripeptide of α-MSH, as a free acid
Eyeseryl®
Acetyl Tetrapeptide-5, an N-acetylated tetrapeptide
3-mer
Palmitoyl Tripeptide-5 (Pal-Lys-Val-Lys)
The dipeptide β-alanyl-L-histidine
4-mer
Acetyl Tetrapeptide-2 (Ac-Lys-Asp-Val-Tyr)
Palmitoyl Tripeptide-8, a palmitoylated, amidated tripeptide
Acetyl Dipeptide-1 Cetyl Ester, an acetylated Tyr-Arg dipeptide ester
2-mer
Dipeptide-2, the dipeptide valyl-tryptophan
Tripeptide-10 Citrulline (Lys-Asp-Ile-Cit-NH2)
6-mer
Hexapeptide-11 (Phe-Val-Ala-Pro-Phe-Pro)
6-mer
Hexapeptide-9 (Gly-Pro-Gln-Gly-Pro-Gln)
4-mer
Palmitoyl Tetrapeptide-10 (Pal-Lys-Thr-Phe-Lys)
Acetyl Hexapeptide-30, an N-acetylated synthetic hexapeptide
Acetyl Hexapeptide-1, an N-acetylated synthetic hexapeptide
Nonapeptide-1, an amidated synthetic nonapeptide
The studies recorded in our product data for the products of this topic (checked 2026-10-09): who led the study or which trial it was, the year, the journal and what was examined. They show what has been researched with each molecule, not results for the vials we supply.
| Product | First author / trial | Year | Journal | What was studied | Record |
|---|---|---|---|---|---|
| Palmitoyl Pentapeptide-4 | Robinson LR | 2005 | Int J Cosmet Sci | Palmitoyl pentapeptide-4 on photoaged facial skin, split-face and placebo-controlled | PubMed 18492182 |
| Palmitoyl Pentapeptide-4 | Choi YL | 2014 | Biomol Ther (Seoul) | Stability of KTTKS and palmitoyl-KTTKS in skin and their permeation in vitro | PubMed 25143811 |
| AHK-Cu | Pyo HK | 2007 | Arch Pharm Res | A tripeptide–copper complex on human hair follicles and dermal papilla cells in vitro | PubMed 17703734 |
| GHK-Cu | Pickart L | 1980 | Nature | The plasma tripeptide GHK and the uptake of copper into cells | PubMed 7453802 |
| GHK-Cu | Pickart L | 2015 | Biomed Res Int | Review of GHK and the cellular pathways of skin regeneration | PubMed 26236730 |
| GHK-Cu | Pickart L | 2018 | Int J Mol Sci | Review of GHK-Cu read against gene-expression data | PubMed 29986520 |
| KPV | Pawar K | 2017 | J Pharm Sci | Passage of KPV through excised human skin, with microporation and iontophoresis compared | PubMed 28343991 |
| KPV | Dalmasso G | 2008 | Gastroenterology | Uptake of KPV through the PepT1 transporter, in intestinal cells and mouse colitis models | PubMed 18061177 |
| KPV | Xiao B | 2017 | Mol Ther | KPV carried in hyaluronic-acid nanoparticles, in a mouse colitis model | PubMed 28143741 |
| KPV | Luger TA | 2007 | Ann Rheum Dis | Review of α-MSH-related peptides, including the C-terminal tripeptide | PubMed 17934097 |
Every lot of a stocked product has its own batch COA. Ask for the COA of the batch you are quoted before you order: the lot number on it is the lot we ship.
What the COA reportsPalmitoyl Pentapeptide-4, Acetyl Octapeptide-3, AHK-Cu, GHK-Cu, KPV — each with catalogue codes, kits of 10 vials from 1 kit, and a batch COA for every lot. The others on this page are quoted on request.
Because a chemical name and a sequence identify a peptide without ambiguity, while a trade name belongs to its owner. Trade names are shown with ® and their owner; we are not affiliated with any of them.
KPV, the tripeptide Lys-Pro-Val, sits with the other skin-research peptides because part of its literature concerns skin — an ex vivo study of how it passes through human skin. It is stocked in kits of ten vials.
Yes. Each peptide and strength starts at one kit, and a single written quotation can cover peptides from every group and every topic.
Name the products, strengths and number of kits, and your country. One written quote can cover several products — we reply within 24 hours.
