Batch COABatch COA
PTD-DBM 1 mg
- Tests:
- HPLC purity · MS identity
- Source:
- Lot release certificate
Full, clear copy from sales — ask by product and strength.
Test it yourself. If it fails, you get a full refund.
Independent test fails? Full refund.
Independent test fails? Full refund.
10 vials per kit, from 1 kit per product and strength. We reply to every quote request within 24 hours. How quotes work →
10 vials per kit · from 1 kit · reply within 24 hours Quotes →
10 vials per kit · from 1 kit Quotes →
Designed 25-residue peptide: octa-arginine, glycine linker, Dishevelled-binding motif
Research topic: Hair · group: Hair-follicle research peptides
PTD-DBM is a designed peptide of 25 residues built from three parts: eight arginines that carry it into cells (a protein transduction domain), four glycines as a linker, and a 13-residue Dishevelled-binding motif. It was made to compete with the protein CXXC5 for binding to Dishevelled, one of the steps of Wnt/β-catenin signalling. Both cysteines are free thiols; the full sequence is in the fact table. It is the dedicated peptide of our hair research page: the papers in our product data examine CXXC5 and Wnt/β-catenin signalling in skin wounds, in hair follicles of mouse models and in human dermal papilla cells. It has not been approved as a medicine.
The COA of every lot of PTD-DBM reports:
Ask for the COA of the batch you are quoted; the batch number on it is the batch we ship.
Each picture is the first page at low resolution, with numbers, dates and signatures covered, so the small print cannot be read. The full, clear copy comes from sales — ask for it by product and strength.
Batch COABatch COA
Full, clear copy from sales — ask by product and strength.
All batch COAs and test reports we show: Batch COA page.
Independent test fails? Full refund. How the refund works
| Field | Value | Source |
|---|---|---|
| Chemical name | PTD-DBM | Our product table |
| Other names | CXXC5-Dvl competitor peptide | Our product table |
| Sequence | H-RRRRRRRR-GGGG-RKTGHQICKFRKC-OH (H-Arg8-Gly4-Arg-Lys-Thr-Gly-His-Gln-Ile-Cys-Lys-Phe-Arg-Lys-Cys-OH; both Cys as FREE thiols, no disulfide) | Our product table |
| Molecular formula | C124H225N61O28S2 | Our product table |
| Molecular weight | 3082.6 g/molReduced form (two free thiols), as the formula shown | Our product table |
| CAS number | 1609454-11-6 | Our product table |
| Strengths (per vial) | 1 mg | Our product table |
| Kit and minimum order | 10 vials per kit · from 1 kit per strength | Our product table |
| Form | Lyophilized powder | Our product table |
| Catalogue codes | 1 mg: PTD1 | Our product table |
| Purity specification | ≥ 99.0% (HPLC)Specification; the measured value is on the COA of the lot. | Our product table |
| Appearance | White to off-white lyophilized powder | Our product table |
| Storage | Store at 2–8 °C, protected from light and moisture | Our product table |
| Batch COA | HPLC purity · MS identity · endotoxin · fill — every lot | Our batch COA |
Product-table values checked 2026-10-09. The measured values of a lot are on its COA.
| First author / trial | Year | Journal | What was studied | Record |
|---|---|---|---|---|
| Lee SH | 2015 | J Exp Med | CXXC5 in skin-wound models, and the PTD-DBM peptide that blocks its binding to Dishevelled | PubMed 26056233 |
| Lee SH | 2017 | J Invest Dermatol | CXXC5 in human balding scalp, in dermal papilla cells and in CXXC5-deficient mice | PubMed 28595998 |
| Ryu YC | 2023 | Cells | CXXC5 and prostaglandin D2 in models of DHT-induced androgenetic alopecia | PubMed 36831222 |
| Mehta A | 2025 | Cells | Review of follicle neogenesis and Wnt/β-catenin signalling | PubMed 40497955 |
Studies recorded in our product data (checked 2026-10-09). They show what has been researched with this molecule — the materials and models of each study — and are not a statement about the vials we supply.
What to put in your quote request
With these facts the first reply can carry the unit price per kit, shipping and lead time.
The octa-arginine is a protein transduction domain: in the design paper it carries the Dishevelled-binding motif into cells. The four glycines keep the two parts apart.
No. Our product table records both cysteines as free thiols, without a disulfide bond; the formula and molecular weight in the fact table refer to that reduced form.
One kit is 10 vials of the same product at the same strength. Each vial holds the stated amount, for example 10 mg of lyophilized peptide; the few solutions are stated per vial in mg or ml. 1 kit per product and strength. One order can combine several products and strengths, each from 1 kit.
HPLC purity, MS identity, endotoxin and fill, on the COA of every lot of a stocked peptide. The COA carries the lot number, so you can match it to the vials you receive. Yes. Ask for the COA of the batch you are quoted; the batch number on that COA is the batch we ship.
In writing, per request. Prices are tiered by the number of kits of each peptide and strength; the quotation gives the unit price per kit, the shipping cost and the lead time. We reply within 24 hours.
Because listings describe different forms: a free peptide or a salt (acetate, TFA), a copper complex or its free peptide, one peptide or a two-peptide material — and some registries keep older numbers. Each product page says which form its values refer to; the COA of the lot is the reference.
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