Test it yourself. If it fails, you get a full refund.
Independent test fails? Full refund.
Independent test fails? Full refund.
10 vials per kit, from 1 kit per product and strength. We reply to every quote request within 24 hours. How quotes work →
10 vials per kit · from 1 kit · reply within 24 hours Quotes →
10 vials per kit · from 1 kit Quotes →
Triple GIP, GLP-1 and glucagon receptor agonist peptide (LY3437943)
Research topic: Body & metabolism · group: GLP-1 class and amylin analogues
Retatrutide, development code LY3437943, is a synthetic peptide of 39 residues with agonist activity at three receptors: GIP, GLP-1 and glucagon. Its sequence holds two 2-aminoisobutyric acid residues and an α-methyl-leucine, ends in a serinamide, and carries a C20 diacid albumin-binding side chain on lysine 17. It is investigational and has not been approved as a medicine anywhere; we supply it as research material. The literature in our product data starts with the discovery paper, which combined cell, mouse and first human data, and continues with randomised trials, among them a substudy on body composition.
The COA of every lot of Retatrutide reports:
Ask for the COA of the batch you are quoted; the batch number on it is the batch we ship.
Each picture is the first page at low resolution, with numbers, dates and signatures covered, so the small print cannot be read. The full, clear copy comes from sales — ask for it by product and strength.
Batch COARetatrutide 2 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Batch COARetatrutide 5 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Batch COARetatrutide 10 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Batch COARetatrutide 12 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Batch COARetatrutide 15 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Batch COARetatrutide 16 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Batch COARetatrutide 20 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Batch COARetatrutide 24 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Batch COARetatrutide 30 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Batch COARetatrutide 40 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Batch COARetatrutide 50 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Batch COARetatrutide 60 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Third-partyRetatrutide 50 mg
HPLC purity · MS identity
Third-party laboratory, Tianjin
Full, clear copy from sales
Customer-sharedRetatrutide 20 mg
Purity · Content per vial
Janoshik (independent laboratory)
Full, clear copy from sales
Customer-sharedRetatrutide 60 mg
Purity · Content per vial
Janoshik (independent laboratory)
Full, clear copy from sales
All batch COAs and test reports we show: Batch COA page.
Independent test fails? Full refund. How the refund works
| Field | Value | Source |
|---|---|---|
| Chemical name | Retatrutide | Our product table |
| Other names | Reta · LY3437943 · Triple G | Our product table |
| Molecular formula | C221H342N46O68 | Our product table |
| Molecular weight | 4731.3 g/mol | Our product table |
| CAS number | 2381089-83-2 | Our product table |
| Strengths (per vial) | 2 mg, 5 mg, 10 mg, 12 mg, 15 mg, 16 mg, 20 mg, 24 mg, 30 mg, 40 mg, 50 mg, 60 mg, 80 mg, 100 mg | Our product table |
| Kit and minimum order | 10 vials per kit · from 1 kit per strength | Our product table |
| Form | Lyophilized powder | Our product table |
| Catalogue codes | 2 mg: RT2 · 5 mg: RT5 · 10 mg: RT10 · 12 mg: RT12 · 15 mg: RT15 · 16 mg: RT16 · 20 mg: RT20 · 24 mg: RT24 · 30 mg: RT30 · 40 mg: RT40 · 50 mg: RT50 · 60 mg: RT60 · 80 mg: RT80 · 100 mg: RT100 | Our product table |
| Purity specification | ≥ 99.0% (HPLC)Specification; the measured value is on the COA of the lot. | Our product table |
| Appearance | White to off-white lyophilized powder | Our product table |
| Storage | Store at 2–8 °C, protected from light and moisture | Our product table |
| Batch COA | HPLC purity · MS identity · endotoxin · fill — every lot | Our batch COA |
| Third-party report | HPLC purity + MS identity by a third-party laboratory in Tianjin, on a 50 mg sample — first-page preview on this page; complete report from sales | Report previews on this page |
| Report shared by a customer | Purity + Content per vial by an independent laboratory, on 20 mg and 60 mg samples — first-page preview on this page; complete report from sales | Report previews on this page |
Product-table values checked 2026-10-09. The measured values of a lot are on its COA.
| First author / trial | Year | Journal | What was studied | Record |
|---|---|---|---|---|
| Coskun T | 2022 | Cell Metab | Discovery of LY3437943: cell and mouse pharmacology and a first human study | PubMed 35985340 |
| Jastreboff AM | 2023 | N Engl J Med | Phase 2 trial in adults with obesity | PubMed 37366315 |
| Rosenstock J | 2023 | Lancet | Phase 2 trial in people with type 2 diabetes | PubMed 37385280 |
| Coskun T | 2025 | Lancet Diabetes Endocrinol | Body-composition substudy of a phase 2 trial in type 2 diabetes | PubMed 40609566 |
Studies recorded in our product data (checked 2026-10-09). They show what has been researched with this molecule — the materials and models of each study — and are not a statement about the vials we supply.
What to put in your quote request
With these facts the first reply can carry the unit price per kit, shipping and lead time.
It adds the glucagon receptor: retatrutide is a triple agonist (GIP, GLP-1, glucagon), tirzepatide a dual one. Both have 39 residues, but their sequences, formulas and CAS numbers differ.
No. It is an investigational molecule; the human studies in our product data are randomised trials. We supply it as a research material.
One kit is 10 vials of the same product at the same strength. Each vial holds the stated amount, for example 10 mg of lyophilized peptide; the few solutions are stated per vial in mg or ml. 1 kit per product and strength. One order can combine several products and strengths, each from 1 kit.
HPLC purity, MS identity, endotoxin and fill, on the COA of every lot of a stocked peptide. The COA carries the lot number, so you can match it to the vials you receive. Yes. Ask for the COA of the batch you are quoted; the batch number on that COA is the batch we ship.
In writing, per request. Prices are tiered by the number of kits of each peptide and strength; the quotation gives the unit price per kit, the shipping cost and the lead time. We reply within 24 hours.
Because listings describe different forms: a free peptide or a salt (acetate, TFA), a copper complex or its free peptide, one peptide or a two-peptide material — and some registries keep older numbers. Each product page says which form its values refer to; the COA of the lot is the reference.
Related peptides
Dual GIP and GLP-1 receptor agonist peptide of 39 residues
Lipidated GLP-1 receptor agonist peptide of 31 residues
Dual glucagon and GLP-1 receptor agonist peptide (BI 456906)
