Test it yourself. If it fails, you get a full refund.
Independent test fails? Full refund.
Independent test fails? Full refund.
10 vials per kit, from 1 kit per product and strength. We reply to every quote request within 24 hours. How quotes work →
10 vials per kit · from 1 kit · reply within 24 hours Quotes →
10 vials per kit · from 1 kit Quotes →
Lys-Pro-Val, the C-terminal tripeptide of α-MSH, as a free acid
Research topic: Skin & ageing · group: Other skin-research peptides
KPV is the tripeptide Lys-Pro-Val with a free carboxylic acid at its C-terminus. It matches residues 11 to 13 of alpha-melanocyte-stimulating hormone (α-MSH), which ends in an amidated valine instead, so the two differ in mass and CAS. On this site KPV belongs to the skin and ageing topic: the papers in our product data follow how the tripeptide crosses excised human skin, how cells take it up through the PepT1 transporter, and how carriers such as hyaluronic-acid nanoparticles change its behaviour in mouse models. The CAS, formula and mass in the fact table refer to the free acid; the COA of each lot confirms what was made.
The COA of every lot of KPV reports:
Ask for the COA of the batch you are quoted; the batch number on it is the batch we ship.
Each picture is the first page at low resolution, with numbers, dates and signatures covered, so the small print cannot be read. The full, clear copy comes from sales — ask for it by product and strength.
Batch COAKPV 5 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Batch COAKPV 10 mg
HPLC purity · MS identity
Lot release certificate
Full, clear copy from sales
Third-partyKPV 10 mg
HPLC purity · MS identity
Third-party laboratory, Tianjin
Full, clear copy from sales
Customer-sharedKPV 10 mg
Purity · Content per vial
Janoshik (independent laboratory)
Full, clear copy from sales
All batch COAs and test reports we show: Batch COA page.
Independent test fails? Full refund. How the refund works
| Field | Value | Source |
|---|---|---|
| Chemical name | KPV | Our product table |
| Other names | alpha-MSH (11-13) | Our product table |
| Sequence | KPV [H-Lys-Pro-Val-OH] | Our product table |
| Molecular formula | C16H30N4O4 | Our product table |
| Molecular weight | 342.44 g/molFree acid, as the formula shown | Our product table |
| CAS number | 67727-97-3 | Our product table |
| Strengths (per vial) | 5 mg, 10 mg, 20 mg | Our product table |
| Kit and minimum order | 10 vials per kit · from 1 kit per strength | Our product table |
| Form | Lyophilized powder | Our product table |
| Catalogue codes | 5 mg: KP5 · 10 mg: KP10 · 20 mg: KP20 | Our product table |
| Purity specification | ≥ 99.0% (HPLC)Specification; the measured value is on the COA of the lot. | Our product table |
| Appearance | White to off-white lyophilized powder | Our product table |
| Storage | Store at 2–8 °C, protected from light and moisture | Our product table |
| Batch COA | HPLC purity · MS identity · endotoxin · fill — every lot | Our batch COA |
| Third-party report | HPLC purity + MS identity by a third-party laboratory in Tianjin, on a 10 mg sample — first-page preview on this page; complete report from sales | Report previews on this page |
| Report shared by a customer | Purity + Content per vial by an independent laboratory, on a 10 mg sample — first-page preview on this page; complete report from sales | Report previews on this page |
Product-table values checked 2026-10-09. The measured values of a lot are on its COA.
| First author / trial | Year | Journal | What was studied | Record |
|---|---|---|---|---|
| Pawar K | 2017 | J Pharm Sci | Passage of KPV through excised human skin, with microporation and iontophoresis compared | PubMed 28343991 |
| Dalmasso G | 2008 | Gastroenterology | Uptake of KPV through the PepT1 transporter, in intestinal cells and mouse colitis models | PubMed 18061177 |
| Xiao B | 2017 | Mol Ther | KPV carried in hyaluronic-acid nanoparticles, in a mouse colitis model | PubMed 28143741 |
| Luger TA | 2007 | Ann Rheum Dis | Review of α-MSH-related peptides, including the C-terminal tripeptide | PubMed 17934097 |
Studies recorded in our product data (checked 2026-10-09). They show what has been researched with this molecule — the materials and models of each study — and are not a statement about the vials we supply.
What to put in your quote request
With these facts the first reply can carry the unit price per kit, shipping and lead time.
No. KPV is three residues long and α-MSH thirteen. KPV corresponds to the last three (Lys-Pro-Val) but carries a free acid where α-MSH carries an amide, so its formula, mass and CAS number are its own.
Because part of its literature concerns skin: Pawar and colleagues (2017) measured how it passes through excised human skin, with microporation and iontophoresis compared. The other studies in our product data used cells and mouse models.
One kit is 10 vials of the same product at the same strength. Each vial holds the stated amount, for example 10 mg of lyophilized peptide; the few solutions are stated per vial in mg or ml. 1 kit per product and strength. One order can combine several products and strengths, each from 1 kit.
HPLC purity, MS identity, endotoxin and fill, on the COA of every lot of a stocked peptide. The COA carries the lot number, so you can match it to the vials you receive. Yes. Ask for the COA of the batch you are quoted; the batch number on that COA is the batch we ship.
In writing, per request. Prices are tiered by the number of kits of each peptide and strength; the quotation gives the unit price per kit, the shipping cost and the lead time. We reply within 24 hours.
Because listings describe different forms: a free peptide or a salt (acetate, TFA), a copper complex or its free peptide, one peptide or a two-peptide material — and some registries keep older numbers. Each product page says which form its values refer to; the COA of the lot is the reference.
Related peptides
3-mer
Copper(II) complex of the tripeptide Gly-His-Lys
3-mer
Copper(II) complex of the tripeptide Ala-His-Lys
13-mer
Afamelanotide: a linear 13-residue analogue of α-MSH
